Bone-RADS Calculator v. 2023

ACR's Bone Reporting and Data System for Bone Tumor Risk Stratification and Management (BONE RADS ™), released October 2023

bone-RADS
Can the bony lesion be fully assessed?
Is there a pathological fracture?
Is there evidence of extra-osseous soft tissue mass?
Does the patient have a known primary cancer?
How is the lesion’s margination / zone of transition?
Is there periosteal reaction?
Is there endosteal scalloping?

Score & recommendations:

Bone-RADS 0. Recommend further evaluation with additional radiographic views or CT/MRI.

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Incompletely characterized, Risk cannot be adequately predicted

Score & recommendations:

Bone-RADS 1. If patient is asymptomatic, consider work up to be complete or alternatively, continue annual surveillance to ensure expected stability. If patient is symptomatic or clinical presentation changes, consider orthopedic oncology referral and further evaluation with CT/MRI.

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Very low risk of malignancy (Pathognomonic benign bone lesion)

Score & recommendations:

Bone-RADS 2. Recommend follow-up imaging in 3-6m vs. further evaluation with CT/MRI. Consider orthopedic oncology referral for surveillance or treatment of benign tumor.

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Low risk of malignancy (probably benign)

Score & recommendations:

Bone-RADS 3. Recommend orthopedic oncology referral and further evaluation with CT, MRI, or bone scan.

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Intermediate risk of malignancy (potentially malignant)

Score & recommendations:

Bone-RADS 4. Recommend orthopedic oncology referral and further evaluation with CT, MRI, or bone scan.

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High risk of malignancy (malignant until proven otherwise)

More about the Bone-RADS Calculator

The Bone Reporting and Data System (Bone-RADS™), introduced by the American College of Radiology (ACR), provides a standardized method for evaluating and managing bone lesions that may be neoplastic. The Bone-RADS calculator helps radiologists assess solitary bone lesions on radiographs, CT, or MRI, offering structured criteria to estimate malignancy risk and guide clinical decisions. This standardized tool improves diagnostic confidence, supports clinical communication, and reduces ambiguity in reporting potentially malignant bone lesions.

Purpose and Use of Bone-RADS™

Bone-RADS™ is designed to be used in the assessment of incidental or suspicious bone lesions discovered during routine imaging. Its goal is to stratify lesions by risk level, allowing radiologists to provide actionable and consistent recommendations. The calculator assigns a Bone-RADS™ category based on key imaging features such as lesion margin, matrix mineralization, periosteal reaction, and associated soft tissue findings. It can be used across various clinical contexts, including orthopedic, oncologic, and emergency imaging scenarios.

Bone-RADS™ Risk Categories and Suggested Actions

The classification system includes four main risk levels:

  • Bone-RADS™ 1 – Very Low Risk: Classic benign findings like bone islands (enostoses) or fibrous cortical defects.
    Action: No additional imaging or follow-up required.
  • Bone-RADS™ 2 – Low Risk: Probably benign lesions without conclusive features. Examples include non-aggressive sclerotic or lytic lesions.
    Action: Cross-sectional imaging (e.g., MRI) recommended for further characterization.
  • Bone-RADS™ 3 – Intermediate Risk: Indeterminate lesions, such as well-defined but atypical lucent lesions or those with mild periosteal reaction.
    Action: Serial imaging at 6, 6, and 12 months to assess for interval growth or evolution.
  • Bone-RADS™ 4 – High Risk: Imaging suggests possible malignancy — features like ill-defined margins, aggressive periosteal reactions, or soft tissue mass.
    Action: Prompt biopsy and/or referral to orthopedic oncology or musculoskeletal specialists is advised.

Benefits of Using the Bone-RADS Calculator

Integrating the Bone-RADS calculator into radiological practice provides several key benefits:

  • Improved Consistency: Ensures uniform lesion classification across institutions and radiologists.
  • Streamlined Management: Links imaging appearance directly with clinical recommendations, reducing ambiguity.
  • Enhanced Reporting Quality: Facilitates comprehensive and structured radiology reports, aiding referring physicians.
  • Educational Resource: Supports learning and professional development for radiologists, residents, and other clinicians involved in musculoskeletal imaging.

Bone-RADS™ in Clinical Context

While Bone-RADS™ is not intended to replace clinical judgment or histopathological analysis, it serves as a valuable adjunct in evaluating bone lesions, particularly those discovered incidentally. The system contributes to better triaging of patients, appropriate use of follow-up imaging, and earlier identification of malignancies requiring intervention.

The Bone-RADS calculator on this page is based on published criteria from the ACR and is designed to be used by trained medical professionals. For additional details, updates, and training materials, visit the official ACR Bone-RADS™ page.

2 Comments

  1. Avatar of Marek Marek says:

    It seems that this calculator incorrectly assigns 4 points for a soft tissue mass, while according to the ACR’s page for Bone-RADS it should assign 2 points only. May you please verify this and fix the bug? Thank you.

    • Avatar of Pooyan Khalighinejad Pooyan Khalighinejad says:

      Hello Dr. Marek,
      Thank you so much for bringing this error to my attention. The bug has been fixed!
      I appreciate your feedback.

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