Spleen Volume & Index (Ultrasound, CT, MRI)
Calculate the splenic volume and index, as well as upper limit of normal for spleen's volume and length based on height and sex.
Splenic Index= ML x W x T
Splenic Volume=π/6× ML ×W × D
Revised formula ² for Splenic Volume for sonographic measurements = π/6 × W × D × ((ML + CCL) / 2)
Expected volume/length based on sex and height is calculated based on formula by Chow et al ¹.
ML= Maximum Length
CCL = Craniocaudal Length (most superior to most inferior aspect)
W= Width
D=Depth
Reference:
- Chow KU, Luxembourg B, Seifried E, Bonig H. Spleen Size Is Significantly Influenced by Body Height and Sex: Establishment of Normal Values for Spleen Size at US with a Cohort of 1200 Healthy Individuals. Radiology. 2016;279(1):306-313. doi:10.1148/radiol.2015150887
- Yetter EM, Acosta KB, Olson MC, Blundell K. Estimating splenic volume: sonographic measurements correlated with helical CT determination. AJR Am J Roentgenol. 2003;181(6):1615-1620. doi:10.2214/ajr.181.6.1811615