Lung-RADS ® 2022

Lung Imaging Reporting and Data System A quality assurance tool designed to standardize lung cancer screening CT by ACR.

Please note:

  • This calculator does not include the "S modifier". Per Lung-RADS® 2022, the S modifier can be added to any categories for clinically significant or potentially clinically significant findings unrelated to lung cancer. This modifier does not affect the follow-up recommendations.

Lung-RADS
Do any of these apply to the exam?
* Note: Inflammatory/infectious findings may include segmental or lobar consolidation, multiple new nodules (more than six), large solid nodules (≥ 8 mm) appearing in a short interval, and new nodules in certain clinical contexts (eg, immunocompromised patient).
→ Estimated population prevalence: ~1%
→ Recommendation: Comparison to prior chest CT is required. Re-evaluate when the prior scan is available.
→ Estimated population prevalence: ~1%
→ Recommendation: Additional lung cancer screening CT imaging needed.
→ Estimated population prevalence: ~1%
→ Recommendation: Repeat low-dose chest CT in 1-3 month.

Note: Some findings indicative of an infectious or infectious process may not warrant short-term follow-up (eg, tree-in-bud nodules or new < 3 cm ground glass nodules). These nodules may be evaluated using existing size criteria with a Lung-RADS classification and management recommendation based on the most suspicious finding.
Do you want to evaluate nodules or cysts?

Pulmonary Cysts:

How is the cyst's wall?
How is the formation of the cyst?
Does the cyst show any growth?
Does the cyst show any growth?

Not categorized in LUNG-RADS

Thin-walled unilocular cysts are considered benign and are not scored in LUNG-RADS.
Note that fluid-containing cysts may represent an infectious process and are not classified in Lung-RADS unless other concerning features are identified.
If there are multiple cysts may indicate an alternative diagnosis such as Langerhans cell histiocytosis (LCH) or lymphangioleiomyomatosis (LAM) and are not classified in Lung-RADS unless other concerning features are identified.
→ Estimated population prevalence: ~9%
→ Recommendation: 6-month low-dose chest CT screening
→ Estimated population prevalence: ~4%
→ Recommendation: 3-month low-dose chest CT screening. PET/CT may be considered if there is a ≥ 8 mm solid nodule or solid component
→ Estimated population prevalence: ~2%
→ Recommendation: Management depends on clinical evaluation, patient preference, and the probability of malignancy. Options are:
* Referral for further clinical evaluation, and/or:
* Diagnostic chest CT with or without contrast
* Tissue sampling
* PET/CT may be considered if there is a ≥ 8 mm (≥ 268 mm3) solid nodule or solid component

Pulmonary Nodules:

Does the nodule have any of the benign features below?
→ Estimated population prevalence: ~39%
→ Recommendation: 12-month low-dose chest CT screening
→ Estimated population prevalence: ~39%
→ Recommendation: 12-month low-dose chest CT screening

How is the composition of the nodule?
Does the nodule meet any of the following criteria?
Insert the short axis and long axis diameters to calculate the mean.

Error: Mean diameter of the solid component cannot be larger than the total mean diameter.

Is the nodule growing?
→ Estimated population prevalence: ~45%
→ Recommendation: 12-month low-dose chest CT screening
→ Estimated population prevalence: ~45%
→ Recommendation: 12-month low-dose chest CT screening
→ Estimated population prevalence: ~45%
→ Recommendation: 12-month low-dose chest CT screening
→ Estimated population prevalence: ~45%
→ Recommendation: 12-month low-dose chest CT screening
→ Estimated population prevalence: ~45%
→ Recommendation: 12-month low-dose chest CT screening
→ A ground-glass nodule (GGN) that demonstrates growth over multiple screening exams but does not meet the > 1.5 mm threshold increase in size for any 12-month interval may be classified as Lung-RADS 2 until the nodule meets findings criteria of another category, such as developing a solid component
→ Estimated population prevalence: ~45%
→ Recommendation: 12-month low-dose chest CT screening
→ Estimated population prevalence: ~45%
→ Recommendation: 12-month low-dose chest CT screening
→ Estimated population prevalence: ~45%
→ Recommendation: 12-month low-dose chest CT screening
→ Estimated population prevalence: ~9%
→ Recommendation: 6-month low-dose chest CT screening
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~9%
→ Recommendation: 6-month low-dose chest CT screening
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~9%
→ Recommendation: 6-month low-dose chest CT screening
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~9%
→ Recommendation: 6-month low-dose chest CT screening
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~9%
→ Recommendation: 6-month low-dose chest CT screening
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~4%
→ Recommendation: 3-month low-dose chest CT screening. PET/CT may be considered if there is a ≥ 8 mm solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~4%
→ Recommendation: 3-month low-dose chest CT screening. PET/CT may be considered if there is a ≥ 8 mm solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~4%
→ Recommendation: 3-month low-dose chest CT screening. PET/CT may be considered if there is a ≥ 8 mm solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~4%
→ Recommendation: 3-month low-dose chest CT screening. PET/CT may be considered if there is a ≥ 8 mm solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~4%
→ Recommendation: 3-month low-dose chest CT screening. PET/CT may be considered if there is a ≥ 8 mm solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~4%
→ Recommendation: 3-month low-dose chest CT screening. PET/CT may be considered if there is a ≥ 8 mm solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~4%
→ Recommendation: 3-month low-dose chest CT screening. PET/CT may be considered if there is a ≥ 8 mm solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~2%
→ Recommendation: Management depends on clinical evaluation, patient preference, and the probability of malignancy. Options are:
* Referral for further clinical evaluation, and/or:
* Diagnostic chest CT with or without contrast
* Tissue sampling
* PET/CT may be considered if there is a ≥ 8 mm (≥ 268 mm3) solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~2%
→ Recommendation: Referral for further clinical evaluation
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~2%
→ Recommendation: Management depends on clinical evaluation, patient preference, and the probability of malignancy. Options are:
* Referral for further clinical evaluation, and/or:
* Diagnostic chest CT with or without contrast
* Tissue sampling
* PET/CT may be considered if there is a ≥ 8 mm (≥ 268 mm3) solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~2%
→ Recommendation: Management depends on clinical evaluation, patient preference, and the probability of malignancy. Options are:
* Referral for further clinical evaluation, and/or:
* Diagnostic chest CT with or without contrast
* Tissue sampling
* PET/CT may be considered if there is a ≥ 8 mm (≥ 268 mm3) solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~2%
→ Recommendation: Management depends on clinical evaluation, patient preference, and the probability of malignancy. Options are:
* Referral for further clinical evaluation, and/or:
* Diagnostic chest CT with or without contrast
* Tissue sampling
* PET/CT may be considered if there is a ≥ 8 mm (≥ 268 mm3) solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~2%
→ Recommendation: Management depends on clinical evaluation, patient preference, and the probability of malignancy. Options are:
* Referral for further clinical evaluation, and/or:
* Diagnostic chest CT with or without contrast
* Tissue sampling
* PET/CT may be considered if there is a ≥ 8 mm (≥ 268 mm3) solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~2%
→ Recommendation: Management depends on clinical evaluation, patient preference, and the probability of malignancy. Options are:
* Referral for further clinical evaluation, and/or:
* Diagnostic chest CT with or without contrast
* Tissue sampling
* PET/CT may be considered if there is a ≥ 8 mm (≥ 268 mm3) solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~2%
→ Recommendation: Management depends on clinical evaluation, patient preference, and the probability of malignancy. Options are:
* Referral for further clinical evaluation, and/or:
* Diagnostic chest CT with or without contrast
* Tissue sampling
* PET/CT may be considered if there is a ≥ 8 mm (≥ 268 mm3) solid nodule or solid component
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.
→ Estimated population prevalence: ~2%
→ Recommendation: Management depends on clinical evaluation, patient preference, and the probability of malignancy. Options are:
* Referral for further clinical evaluation, and/or:
* Diagnostic chest CT with or without contrast
* Tissue sampling Note: Slow-growing nodules may not have increased metabolic activity on PET/CT; therefore, biopsy, if feasible, or surgical evaluation may be the most appropriate management recommendation.
Attention: Any category 3 or 4 nodules with additional imaging findings that increase the suspicion of lung cancer  (such as spiculation, lymphadenopathy, frank metastatic disease, a GGN that doubles in size in 1 year, etc.), the score should be increased to Category 4X.

1 Comment

  1. Al Katz says:

    I could not resist commenting. Exceptionally well written!

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